Is Mirtazapine (Remeron) Safe for Dogs?
Why it’s a problem
Vets do prescribe mirtazapine as an appetite stimulant for dogs, but at calculated doses using appropriate formulations. Human tablets are large, and an accidental dose can cause heavy sedation, wobbliness, and vomiting. Combined with certain antidepressants or pain medications, it can contribute to serotonin syndrome, a potentially serious reaction.
How to keep your pet safe
Keep the bottle closed and out of reach, and never give your own tablets to stimulate a dog’s appetite. If your dog has prescribed mirtazapine, tell the vet about every other drug and supplement it receives. Store weekly organizers where a dog cannot reach them.
Warning signs to watch for
Severe drowsiness, stumbling, vomiting, drooling, vocalizing, tremors, fast heartbeat; serotonin syndrome signs include agitation, tremors, and high body temperature.
When to call the vet
Call a vet or pet poison hotline after any accidental ingestion, reporting all other medications the dog takes. Single-tablet exposures often need monitoring, but combinations raise the risk and warrant a clinic visit. Never mix human antidepressants with prescribed pet medications.
Common questions
My vet gives my dog mirtazapine — so why is eating my Remeron bad?
Veterinary dosing is calculated for your dog and checked against its other medications. Human tablets are large, and an unsupervised dose can cause heavy sedation or serotonin problems.
What is serotonin syndrome in dogs?
It is a drug reaction — agitation, tremors, fast heart rate, and high body temperature — that can occur when serotonergic drugs stack. Any overdose involving mirtazapine deserves an immediate call to a vet or pet poison hotline.
More medications hazards for dogs
This page is general educational information, not a substitute for professional veterinary advice. Every pet is different — if your animal ate or touched something concerning, contact your veterinarian or a pet poison hotline right away. In the US: Pet Poison Helpline (855) 764-7661, ASPCA Animal Poison Control (888) 426-4435 (fees may apply).